The title says client, but it's really not clear to me what the actual transactions are. If it is client and he just moved the ECOM100, I don't think the peer table needs to be changed. If it is actually server, it's probably just that the requests are out of range. As a server, requests go to DLxx memory which is much smaller than DL's native memory by default.
We really need more detail Henry. What comm requests are failing, and is the Do-more side originating or receiving the request?