If you are using ECWX/ECRX IBoxes in the DL260, you can address multiple slaves pretty easily. You can, for example, put multiple ones on the same rung and just enable the rung. The ECWX/ECRX IBoxes have a built-in "token passing" and will cycle through them as fast as possible. The backplane is the bottleneck. During the communication cycle, if I remember correctly with a DL260, each scan can pass about 128 bytes... sometimes more, I believe.
Anyway, the ECOM100 can maintain up to 12 simultaneous Modbus TCP connections.