BobO, based on your response I looked at comms links. I had an ethernet ECOM module in my links which was unplugged when I was noticing the long wait times. I deleted the ECOM link and the latency issues seem to go away. Does this mean that at any time DMD can't find links that there is the potential for these long wait times?
I wouldn?t think that bad links would have a specific impact, other than possibly changing Windows networking behavior, which is where I would guess the problem is. All a link contains is the comm device settings, but at startup we attempt to talk to all of them just to see if they are there. If there is a busted connection, Windows may be attempting to hit a network adapter (virtual, wireless, etc) that is causing the delays.
The other big slowdown i see on occasion is when I have multiple designer sessions open, and one is online to a device that isn?t answering. Pretty common in my world (while developing), but that doesn?t really break anything, just slows the comm down on the functional session. Certainly nothing like you are describing.