i installed the software on my access point which is a virtual computer and i can open it anywhere where i work on any other access point.
as soon as i open the do-more sim i get what shows on the picture
i do use click and c more direct soft 5 software and they all work.
Rel 2.2 now installs to Program Files. Hence, the Simulator data files are now located in the "public documents"\Do-more\Designer2_2\bin folder. You need to create that folder on whatever PC you are running the Simulator on.
There may be other features that act strangely (Live Update, Help, et.al.). The software was not developed to run on multiple PCs off a central server. It may have "worked", but your installation is a little different than typical installations. Caveat Emptor.